W filmie wystąpiły legendarne gwiazdy bluesa, James Brown, Cab Calloway, Ray Charles i Aretha Franklin, którym partnerują John Candy, Carrie Fisher, Henry Gibson i Steve Lawrence.
Jake Blues rejoins with his brother Elwood after being released from prison, but the duo has just days to reunite their old R&B band and save the Catholic home where the two were raised, outrunning the police as they tear through Chicago.
